I am not sure Ana Lucia is a trans character (unless I missed something in the two previous episodes, which I missed while on holiday). It's more like these fans speaking out have such preconceived notions about women (and about trans apparently) they think a woman can't be strong and angry and violent without becoming a man (or literally being a man) and think trans is an insult.

I love Rodriguez's rock hard female characters, especially the female boxer and the street racer. Oh, pairing MR and Vin Diesel was the best damn idea for a movie couple ever. Humina.